I was wondering if there was any real benefit to mains conditioning/regeneration myself. Being in a university environment I thought I'd look up researchers from Electrical Engineering to see if anyone might have an idea. I was pleased to find someone with a PhD specifically in audio amplifier design. I have copied my question below:
".......One thing I have thought about is the grey area of 'mains conditioning' or 'mains filtering'. As mentioned though, I know nothing about electrical design, so I thought I would see who was in Electrical Engineering to see if anyone could help with my ignorance. I was very pleased to note your area of interest in the design of audio amplifiers, so thought who better to ask. I was hoping you wouldn't mind me asking your thoughts on mains conditioners, e.g. products from Isotek etc? To me, it makes sense that a "dirty" electrical supply can effect the sound and that filtering and conditioning can improve the sound (and lifetime of the components). I certainly get "squeeks" and "pops" audible through my TV when the fridge-freezer compressor initiates. Also, I've seen a few teardowns of these units isotek produce and they look like there's not many components in there given the high cost? If conditioning is of genuine benefit, is there any reason to purchase one of these high end units over a simple surge protector?....." And his response: ".......In general, I think that “HiFi” mains conditioners and associated products tend to be poor value for money.
An amplifier that makes squeaks and pops on major power line disturbances such as compressors starting and stopping is just poorly designed and is probably due to input signal lines being routed too close to power lines, resulting in cross-coupling between the two (i.e. a “spike” on the power line results on a spike in the input signal to the amplifier, which is dutifully amplified resulting in the audible disturbance). One would hope that a proper HiFi amplifier would not suffer from such a thing. Here, a “standard” (i.e. not designed for HiFi) mains adaptor plug with built-in surge protector may help to prevent any power line “spikes” reaching the power input of an amplifier.
In terms of smaller-amplitude “noise” that may be found on the mains, it is highly unlikely that removing said noise makes a genuinely significant measurable difference to the sound. However, there is the small matter of the “observer-expectancy” effect to consider. The human brain is a wonderful thing. As part of interpreting sensory inputs and converting them into sensations, your brain uses a wide variety of information to interpret said sensory inputs. This is totally unavoidable and is why proper scientific experiments involving subjective reactions of humans have to be conducted double-blind. If you buy a mains conditioner and install it, your brain knows that you’ve done so. It will then interpret the sensory inputs from your ears accordingly, such that you may well genuinely experience the audio differently to how you experienced it prior to installing the mains conditioner. Not because the mains conditioner has made a genuine objectively-measurable difference to the audio signal, but just because your brain is now processing the information from your ears slightly differently!
I’d suggest you put any money you might have spent on expensive HiFi mains products towards the next pair of speakers you buy. Loudspeakers are, by far, the components with the greatest measurable impact on the sound of your HiFi....." In honesty I asked about mains conditioners rather than regenerators, but I would have thought he would have mentioned if this provided real benefit.