There are new regulations product manufacturers have to comply with in order to distribute MDF based products around the world these days. As well as ROHS compliance, there is also E1 and now E0 grade compliance for MDF based products. E1 restricts the inclusion of Formaldehyde and E0 grade even further. These have specific dates in which to comply. But essentially if speaker makes do not comply, then they will be in trouble by the country specific customs officials tasked with policing the legislation.
CARB is a different regulation which is even more restrictive for California right now, but it is viewed this will spread to the rest of North America soon.
The Formaldehyde in MDF bonds the wood powder together and makes it hard. Unfortunately Formaldehyde substitutes result in softer MDF, less dense and so the stiffness is lower. This then requires better bracing to get good sonic results. It is also much more expensive than the old Formaldehyde MDF grade.