Morning Broner, I'll do my best.
The 'setup' as I have termed it is to do with the nature of speakers like the Opals. They are capable of far higher output and tremendous power bandwidth, particularly at the bass end, not only do they go down below 50hz but the deliver considerable power at such frequencies, unlike most hi-fi speakers. Why else would you need a bass amplifier that produces 387 watts of continuous power?
The energy capabilities of such speakers is pretty formidable and they are really designed for use in an acoustically controlled environment. Pump out that much low frequency energy into a 'normal' room and you will get every window, piece of furniture and pretty much everything else buzzing and booming along with the music.
This is further compounded by the tendency to play these kinds of speakers louder than normal, almost all of the cues that tell you when a hi-fi system is getting loud are absent here, no clipping, dynamic compression or cabinet boom for example. Getting the balance right and the level correct is what I mean when I refer to 'setup'.
The whole nearfield/midfield/farfield thing as applied to monitors is a bit of a nonsense really. In theory a true nearfield monitor would have a different 'polar' response to take account of the fact that the direct sound predominates but in the real world this is rarely done.
These days a 'nearfield monitor' is really just marketing speak for a monitor that simply does not go loud enough to be used at a distance. As it will usually be smaller and much cheaper than a main monitor, the drivers will be smaller and closer together, thus 'integrating' better when listened to close. They will not go as loud as main monitors but if they are close enough that is not a big issue and because they are putting out far less power (energy) into the room, acoustic controll is less of an issue.
There are a few exceptions, serious monitors like the Opals, developed because some producers/engineers like to listen close, are about as near as you can get to proper nearfield speakers, though my preference is to set these up about 10ft from the listening position and in free space.