Hi Joe,
One of the good things about this set is that it works very well straight out of the box. The only changes we made to the settings like colours, contrast, tint, etc were very small and it's not really worth matching the same on your model because of the small differences between panels.
That said, there are some bigger changes to a few of the modes which are well worth making. First is that we stuck with the Standard Picture Mode and we feel that 43RU7470 gives the best image when the Contrast Enhancer is set to Low.
Digital Clean View isn't necessary when you're watching 4K HDR video but it's worth adding as you drop down to 1080p and particularly once the set is upscaling from SD.
The team tends to agree that a Judder Reduction of about 2 or 3 is the best compromise for the Motion settings.
Also, don't forget to head to the Eco menu and switch off any ideas that the TV has about sacrificing performance. So, Ambient Light Detection should be off, along with Energy Saving Mode and Motion Lighting, etc.
Hope that helps.