I have: Cambridge Audio S70 speakers & Cambridge Audio azur 540A amplifier connected via phono to an M-Audio Fast Track USB external sound card, which is connected via USB to my computer. I would say that my amplifier and speakers are sufficiently 'warn-in', and I am using high-quality cables. The 'sample rate and bit depth' properties for the driver, on my computer, are set to the highest settings - '2 channel, 24bit, 44100 Hz (Studio quality)'. For practical reasons, I play most of my music through Spotify Unlimited.
http://i41.tinypic.com/33w30h3.jpg
http://i41.tinypic.com/33w30h3.jpg