I can not say i have personally heard either set up but the LX 01 has a lot going for it. I can tell you pioneer don't make premium products rubbish. I do own pioneer products tv , amp , dvd had a hifi system once , never been disappointed. Don't forget the LX01 is also HDD 250g just right for recording virgin music. The LX01 is available for just under £900. To me the onkyo + q or mission combination would have to be at least twice as good as the LX01 for me to even consider it a serious choice the onkyo /q or mission is no looker is it ?. I have had mission speakers in the past (floorstander 75 somethings and bookshelf for rears) and they were good but i didn't miss them when they went. I also know a mate at work who hadn't had a proper sound system and he went for the pioneer rcs-lx60d last year he loves it and is really happy with it. The choice is yours if it were me i would be more inclined to go with the lx01.