Do not have a great deal of room to work with. I also have a lot of music on a hard drive and may wish to add a turntable in the future. Would this work or would a Rega Brio R/DAC & RS1 system using my mac mini be more effective?
The system you're thinking of should work very well. I'd suggest it would be very neutral with the Audiolab CD player and if space is at a premium the sealed-box design of the AE22's should help. The AE22's were also designed to work atop a mixing desk so placement on a unit, shelf or even bookcase is still viable and in some cases preferable (the mid alignment is aided by the surface underneath due to it's intended placement on a desk, although they also work perfectly well on stands).
From what I can see the CDQ has a few inputs on the back so you may well be able to use a hard-drive and turntable with the built-in preamp, though someone who knows the unit better may be able to advise more clearly on that...
Agreed with Alears - while technically the XLR connection is better, the audible differences are tiny. The AE22 accepts standard phono plugs as well as XLR and comes with a pair of Neutrik connectors should you wish to use your existing cables with the XLR terminals. Don't buy any specialist cables if you go for the AE22's, your "standard" cable will be fine!