Yes, but not from a related socket. The M1's usb plug is connected to one of three usb3 sockets on a pci-e card. There is an external hard drive plugged into the same card but it is not switched on. I tried plugging it into one of the front usb3 sockets (which have no other devices connected) and that didn't make any difference. What did help was buying a V-Link 192 and putting the usb signal into that and from there by AES to the M1. The crackles have pretty much disappeared. An expensive solution but I much prefer the sweeter top end that I now have to the rather abrasive one of the DacMagic+ I had before. However, the DM+ worked beautifully with no crackles in usb mode. I'm keeping fingers crossed that crackles and stutters are now behind me.